Yes. The safety of C.E.T.® VEGGIEDENT® Zen has been tested in dogs, including a group of dogs that received 5x the recommended amount for 28 days:

All dogs consumed all the chews they were given.
No clinical signs were observed in relation to the chews given.
Chews did not affect rectal temperature, body weight or food consumption.
All mean hematology results remained within physiological range; no variations in relation to treatment were recorded.